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社区中、老年人群高血压前期对颈动脉粥样硬化斑块形成的影响
作者: 洪华 王鸿轩 廖焕权 王莹 HONG Hua WANG Hongxuan LIAO Huanquan WANG Ying
单位:中山大学附属第一医院神经科,广州,510080
关键词: 高血压前期 颈动脉 斑块 社区 中老年 Prehypertension Carotid Plaque Community Middle-aged and elderly
分类号:
出版年·卷·期(页码):2009·35·第 12 期(0-0)
摘要:
目的 探讨社区中、老年人群高血压前期与颈动脉粥样硬化斑块形成的关系.方法 分别对942名46~75岁广州社区居民进行问卷调查、体格检查、血生化检验和双侧颈动脉超声检查,根据JNC-7的血压分类标准,比较正常血压(normotension,NT)、高血压前期(prehypertension,Pre-HT)和高血压(hypertension,HT)3亚组人群颈动脉粥样硬化斑块形成的差异.结果 Pre-HT和HT均与高龄、男性、肥胖、血脂异常、吸烟的危险因素相关.控制相关危险因素后,Pre-HT颈动脉粥样硬化斑块形成是NT的2.37倍(95%CI:1.42~3.95,P0.05).与HT相比,Pre-HT颈动脉粥样硬化斑块以低回声斑块较多.结论 高血压前期与颈动脉粥样硬化斑块形成风险增高相关,处于高血压前期的中、老年人群已存在较明显的靶器官损害--颈动脉粥样硬化斑块形成.
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