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神经炎症与阿尔茨海默病的迷茫与前景
作者: 朱飞奇 钱采韵
单位:朱飞奇(郧阳医学院附属太和医院神经内科,十堰,442000)钱采韵(中山大学附属第一医院神经内科)
关键词: 阿尔茨海默病 神经炎症
分类号:
出版年·卷·期(页码):2009·35·第 1 期(0-0)
摘要:
阿尔茨海默病(Aizheimeds disease,AD)的发病机理一商不完伞清楚,老年斑是AD最具特征性的病理改变,在老年斑的周围有大量活化的胶质细胞和大量的炎症因子分泌,因此神经炎症在AD发病机制中的作用一直倍受关注,曾经比较一致的观点认为神经炎症对AD是不利,期望通过抗炎治疗能延缓AD的进展[1],但是最近的临床研究结果却相反,并且越来越多研究认为炎症可能对AD是有利的.
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