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双相抑郁障碍的临床特征研究进展(上)
作者: 徐贵云 唐牟尼 党亚梅
单位:广州市精神病医院;
关键词: 双相障碍 抑郁 临床特征
分类号:
出版年·卷·期(页码):2008·34·第 11 期(0-0)
摘要:
双相障碍发病率高,双相谱系障碍的终生患病率大约3·7%~11·5%,仅双相Ⅰ型和双相Ⅱ型障碍就达约1·3%,而双相抑郁障碍(bipolar depressive disorder,BDD)表现突出,危害更严重,是一种病期长(是躁狂的3倍)、共病率高、复发率高、自杀率高(20%死于自杀)、致残率高的慢性疾病,然而常常不被识别或误诊为单相抑郁障碍(unipolar depressive disorder,UDD),导致治疗不充分和持续残疾[1-4]。调查显示确诊明显延迟,只有20%的患者得到诊断,而31%诊断为UDD,49%没有诊断[3]。双相抑郁障碍(BDD)误诊,除了没有识别和诊断轻躁狂发作外,主要是由于临床症状及生物学异常与单相抑郁症(UDD)相似,但BDD还具有许多可资鉴别的临床特点,如发病年龄早、发作更频繁、病期时间更长、愤怒攻击等[5]。本文对双相抑郁障碍的临床特征进行以下综述。1人口学特征1.1男女性别比例双相障碍的女性/男性比较单相抑郁症低,比例接近。一项国际性的调查[6]发现,单相抑郁症的女/男比(美国为2·6)普遍比双相Ⅰ型障碍(为1·2)高。其他的研究也报道了类似的结果。但是,双相Ⅱ型障碍的...
参考文献:

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Springer 期刊数据库 共找到 1 条

[1] Franco Benazzi,Sanaa Helmi,Lorna Bland. Agitated Depression: Unipolar Bipolar or Both[J]. Annals of Clinical Psychiatry, 2002,14(2) :97~104.
 

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